翻訳と辞書 Words near each other ・ PolyIran ・ Polyisocyanurate ・ Polyjapyx ・ Polykarp Kusch ・ Polykarp Leyser ・ Polykarp Leyser II ・ Polykarp Leyser III ・ Polykarp Leyser IV ・ Polykarp Leyser the Elder ・ Polykastano ・ Polykastro ・ Polykastro F.C. ・ Polykay ・ Polyketide ・ Polyketide synthase ・ Polyketide synthesis cyclase family ・ Polyketone ・ Polyking ・ Polykleitos ・ Polykleitos the Younger ・ Polyknight ・ Polykrikaceae ・ Polykrikos kofoidii ・ PolyL ・ Polylactic acid ・ Polylakko ・ Polylateral Development ・ Polylepion ・ Polylepis ・ Polylepis australis Dictionary Lists mini英和辞書 mini和英辞書 Webster 1913 Latin-English FOLDOC Wikipedia English ウィキペディア

翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Polyketide synthesis cyclase family ： ウィキペディア英語版 Polyketide synthesis cyclase family In molecular biology, the polyketide synthesis cyclase family of proteins includes a number of cyclases involved in polyketide synthesis in a number of actinobacterial species. Aromatic polyketides are assembled by a type II (iterative) polyketide synthase in bacteria. Iterative type II polyketide synthases produce polyketide chains of variable but defined length from a specific starter unit and a number of extender units. They also specify the initial regiospecific folding and cyclisation pattern of nascent polyketides either through the action of a cyclase (CYC) subunit or through the combined action of site-specific ketoreductase and CYC subunits. Additional CYCs and other modifications may be necessary to produce linear aromatic polyketides. The Tetracenomycin polyketide synthesis protein, tcmI, from ''Streptomyces glaucescens'' catalyses an aromatic rearrangement in the biosynthetic pathaway of tetracenomycin C from ''Streptomyces coelicolor''. The protein is a homodimer where each subunit forms a beta-alpha-beta fold belonging to the ferrodoxin fold superfamily. Four strands of antiparallel sheets and a layer of alpha helices create a cavity which was proposed to be the active site. This structure shows strong topological similarity to a polyketide monoxygenase from ''Streptomyces coelicolor'' which functions in the actinorhodin biosynthesic pathway. It was suggested, therefore, that this fold is well suited to serve as a framework for rearrangements and chemical modification of polyaromatic substrates. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Polyketide synthesis cyclase family」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.